Helping you every step of the way with ACTIMMUNE®

Managing treatment for chronic granulomatous disease (CGD) can involve a lot of moving parts. Horizon By Your Side is a patient support program with dedicated team members who take a personalized approach to meeting the unique needs of each patient prescribed ACTIMMUNE® (Interferon gamma-1b). Learn more at HorizonByYourSide.com.

With Horizon By Your Side, you’ll have a support team that includes a dedicated Clinical Nurse Educator (CNE) to guide and support you through every step of your journey. Together, they will:

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Connect: You will be paired with a Clinical Nurse Educator who will be there to support you throughout your treatment when you need it

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Coordinate: The Horizon By Your Side Team will work with you and our healthcare team to make sure non-medical, logistical efforts are coordinated properly

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Champion: Your Clinical Nurse Educator will be your point of contact and help you to build confidence through your treatment

Your Horizon By Your Side support team

Clinical Nurse Educator

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Your Clinical Nurse Educator (CNE) provides you with dedicated, one-on-one support. They work directly with you to answer non-medical, logistical questions and provide support once you have been prescribed ACTIMMUNE® and you have completed enrollment.

Reach out to your Clinical Nurse Educator to help you:

  • Get non-medical educational support
  • Avoid surprises at the start of treatment by talking about what to expect
  • Discuss how your new treatment can fit into your routine and meet your goals
  • Understand financial assistance options
  • Learn about the insurance process
  • Coordinate delivery with the specialty pharmacy to schedule shipments of your medicine
  • Get injection training and support
  • Connect to a sharps disposal program for easy needle and syringe pickup and disposal
  • Receive refill reminders to help you stay on ACTIMMUNE® as your doctor has instructed
  • Connect to advocacy groups for more support and inform you of events in your area

Get the support you deserve

Horizon By Your Side

Enrolling in Horizon By Your Side is easy. Call 1 (877) 305-7704 to get connected. Or sign up through your doctor’s office, who will have the enrollment form and can submit for you after you’ve signed it. You can also visit the Horizon By Your Side site for information specific to CGD and ACTIMMUNE at HorizonByYourSide.com

Important Safety Information

What is ACTIMMUNE® (Interferon gamma-1b) used for?

ACTIMMUNE® is part of a drug regimen used to treat Chronic Granulomatous Disease, or CGD. CGD is a genetic disorder, usually diagnosed in childhood, that affects some cells of the immune system and the body's ability to fight infections effectively. CGD is often treated (though not cured) with antibiotics, antifungals, and ACTIMMUNE.

ACTIMMUNE is also used to slow the worsening of severe, malignant osteopetrosis (SMO). SMO is a genetic disorder that affects normal bone formation and is usually diagnosed in the first few months after birth.

When should I not take ACTIMMUNE?

Don't use ACTIMMUNE if you are allergic to interferon-gamma, E coli-derived products, or any ingredients contained in the product.

What warnings should I know about ACTIMMUNE?

At high doses, ACTIMMUNE can cause (flu-like) symptoms, which may worsen some pre-existing heart conditions.

ACTIMMUNE may cause decreased mental status, walking disturbances, and dizziness, particularly at very high doses. These symptoms are usually reversible within a few days upon dose reduction or discontinuation of therapy.

Bone marrow function may be suppressed with ACTIMMUNE, and decreased production of cells important to the body may occur. This effect, which can be severe, is usually reversible when the drug is discontinued or the dose is reduced.

Taking ACTIMMUNE may cause reversible changes to your liver function, particularly in patients less than 1 year old. Your doctor should monitor your liver function every 3 months, and monthly in children under 1 year.

In rare cases, ACTIMMUNE can cause severe allergic reactions and/or rash. If you experience a serious reaction to ACTIMMUNE, discontinue it immediately and contact your doctor or seek medical help.

What should I tell my healthcare provider?

Be sure to tell your doctor about all the medications you are taking.

Tell your doctor if you:

are pregnant or plan to become pregnant or plan to nurse

have a cardiac condition such as irregular heartbeat, heart failure, or decreased blood flow to your heart

have a history of seizures or other neurologic disorders

have, or have had, reduced bone marrow function. Your doctor will monitor these cells with blood tests at the beginning of therapy and at 3-month intervals on ACTIMMUNE therapy

What are the side effects of ACTIMMUNE?

The most common side effects with ACTIMMUNE are "flu-like" symptoms such as fever, headache, chills, muscle pain, or fatigue, which may decrease in severity as treatment continues. Bedtime administration of ACTIMMUNE may help reduce some of these symptoms. Acetaminophen may be helpful in preventing fever and headache.

    What other medications might interact with ACTIMMUNE?

    Some drugs may interact with ACTIMMUNE to potentially increase the risk of damage to your heart or nervous system, such as certain chemotherapy drugs. Tell your doctor about all other medications you are taking.

    Avoid taking ACTIMMUNE at the same time as a vaccination.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

    The risk information provided here is not comprehensive. To learn more, talk about ACTIMMUNE with your healthcare provider or pharmacist. The FDA-approved product labeling can be found at http://www.ACTIMMUNE.com or 1-866-479-6742.

    Important Safety Information

    What is ACTIMMUNE® (Interferon gamma-1b) used for?

    ACTIMMUNE® is part of a drug regimen used to treat Chronic Granulomatous Disease, or CGD. CGD is a genetic disorder, usually diagnosed in childhood, that affects some cells of the immune system and the body's ability to fight infections effectively. CGD is often treated (though not cured) with antibiotics, antifungals, and ACTIMMUNE.

    ACTIMMUNE is also used to slow the worsening of severe, malignant osteopetrosis (SMO). SMO is a genetic disorder that affects normal bone formation and is usually diagnosed in the first few months after birth.

    When should I not take ACTIMMUNE?

    Don't use ACTIMMUNE if you are allergic to interferon-gamma, E coli-derived products, or any ingredients contained in the product.

    What warnings should I know about ACTIMMUNE?

    At high doses, ACTIMMUNE can cause (flu-like) symptoms, which may worsen some pre-existing heart conditions.

    ACTIMMUNE may cause decreased mental status, walking disturbances, and dizziness, particularly at very high doses. These symptoms are usually reversible within a few days upon dose reduction or discontinuation of therapy.

    Bone marrow function may be suppressed with ACTIMMUNE, and decreased production of cells important to the body may occur. This effect, which can be severe, is usually reversible when the drug is discontinued or the dose is reduced.

    Taking ACTIMMUNE may cause reversible changes to your liver function, particularly in patients less than 1 year old. Your doctor should monitor your liver function every 3 months, and monthly in children under 1 year.

    In rare cases, ACTIMMUNE can cause severe allergic reactions and/or rash. If you experience a serious reaction to ACTIMMUNE, discontinue it immediately and contact your doctor or seek medical help.

    What should I tell my healthcare provider?

    Be sure to tell your doctor about all the medications you are taking.

    Tell your doctor if you:

    are pregnant or plan to become pregnant or plan to nurse

    have a cardiac condition such as irregular heartbeat, heart failure, or decreased blood flow to your heart

    have a history of seizures or other neurologic disorders

    have, or have had, reduced bone marrow function. Your doctor will monitor these cells with blood tests at the beginning of therapy and at 3-month intervals on ACTIMMUNE therapy

    What are the side effects of ACTIMMUNE?

    The most common side effects with ACTIMMUNE are "flu-like" symptoms such as fever, headache, chills, muscle pain, or fatigue, which may decrease in severity as treatment continues. Bedtime administration of ACTIMMUNE may help reduce some of these symptoms. Acetaminophen may be helpful in preventing fever and headache.

      What other medications might interact with ACTIMMUNE?

      Some drugs may interact with ACTIMMUNE to potentially increase the risk of damage to your heart or nervous system, such as certain chemotherapy drugs. Tell your doctor about all other medications you are taking.

      Avoid taking ACTIMMUNE at the same time as a vaccination.

      You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

      The risk information provided here is not comprehensive. To learn more, talk about ACTIMMUNE with your healthcare provider or pharmacist. The FDA-approved product labeling can be found at http://www.ACTIMMUNE.com or 1-866-479-6742.