What is ACTIMMUNE^®?

ACTIMMUNE^® is a bioengineered form of interferon gamma, a protein that acts as a biologic response modifier through stimulation of the human immune system. It is approved by the U.S. Food and Drug Administration for use in children and adults with chronic granulomatous disease (CGD) and severe, malignant osteopetrosis.

Click on the links to the left to learn more about the science of ACTIMMUNE^® and its clinical safety and efficacy in chronic granulomatous disease (CGD) and severe, malignant osteopetrosis.

The most common adverse events observed in patients with CGD were flu-like symptoms (e.g., headache, fatigue, fever, myalgia, and rigors). Similar adverse events were observed in patients with severe malignant osteopetrosis. Please refer to the ACTIMMUNE® Safety section on this Web site for more complete safety information.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of patients.

For U.S. resident use only. The product discussed herein may have different product labeling in different countries. Please see the full U.S. Prescribing Information (pdf file).